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Pomegranate Extract

Pomegranate Extract is a powerful antioxidant containing polyphenols, tannins and anthocyanins. Recent scientific studies suggest that pomegranate may have beneficial effects on cardiovascular disease including atherosclerosis^1-2. These studies showed that carotid artery thickness decreased and cardiac blood flow improved with use of pomegranate. Preliminary evidence also suggests that pomegranate may help reduce levels of cholesterol and systolic blood pressure³.

In addition, pomegranate may help support healthy prostate function^4-7 and may have antibacterial effects against dental plaque⁸.

These statements have not been evaluated by the U.S. Food and Drug Administration. These products are not intended to diagnose, cure or prevent any disease.

References

1. Aviram M et al. Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL oxidation. Clin Nutr. 2004 Jun;23(3):423-33.
2. Kaplan M, Hayek T, Raz A, Coleman R, Dornfeld L, Vaya J, Aviram M. Pomegranate juice supplementation to atherosclerotic mice reduces macrophage lipid peroxidation, cellular cholesterol accumulation and development of atherosclerosis. J Nutr. 2001 Aug;131(8):2082-9.
3. Aviram M, Dornfeld L. Pomegranate juice consumption inhibits serum angiotensin converting enzyme activity and reduces systolic blood pressure. Atherosclerosis 2001 Sep;158(1):195–8.
4. Pomegranates for the prostate and the heart: seeds of hope. Harv Mens Health Watch. 2007 Apr; 11(9):4-5.

5. Seeram NP, Aronson WJ, Zhang Y et al. Subsequently, it has recently been found that pomegranate and its ellagitannin-derived metabolites inhibit prostate cancer growth and localize to the mouse prostate gland. J Agric Food Chem. 2007 Sep 19;55(19):7732-7.
6. N.P. Seeram et al. / Journal of Nutritional Biochemistry 16 (2005) 360–367.
7. Pantuck, A. et al., "Phase II study of pomegranate juice for men with rising prostate-specific antigen following surgery or radiation for prostate cancer.", Clinical Cancer Research, Vol. 12, 4018-4026, July 1, 2006.
8. Menezes SM, Cordeiro LN, Viana GS (2006). "Punica granatum (pomegranate) extract is active against dental plaque". Journal of herbal pharmacotherapy 6 (2): 79–92.

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